Facile synthesis of novel hybrid POSS biomolecules via “Click” reactions

摘要

A novel alkyne-terminated cubic-octameric POSS was synthesised in high yield (82–90%). The X-ray crystal structure revealed intra- and intermolecular hydrogen bonding between the amide groups of the arms. Hybrid biomaterials were synthesised in nearly quantitative yields a click reaction with (i) azido--Fmoc- norleucine and (ii) 3'-azido-3'-deoxythymidine.